Sankhya: The Indian Journal of Statistics
1995, Volume 57, Series B, Pt. 2, pp. 285--297
DETERMINATION OF THE NO-OBSERVED-ADVERSE -EFFECT LEVEL BY THE AIC
TAKASHI YANAGAWA, Kyushu University
YASUKI KIKUCHI, Sesbo College of Technology
SUMMARY. The determination of the no-observed-adverse-effect level (NOAEL) is given, and the procedure for determination of the NOAEL based on the Akaike Information Criterion (AIC) is described in a general situation including dichotomous and categorical response data (ie., severity data), and continuous response data. Examples are given to illustrate the procedure.
AMS subject classification. Primary 62H12; secondary 62P99.
Key words and phrases. Categorical response data, continuous response data, continuation-ratio logic model, environmental health, information criterion, order restriction, toxicology.
Full paper (PDF).